l

 Home l UK Companies l Genomics Topics l Species with sequenced Genomes l Contact

l
Friday 03rd July 2009 01:54 AM This Month's Genome Publications

Genomics refers to the study of genes and their function. Genomics leads to an understanding of the molecular mechanisms of disease, including the complex interplay of genetic and environmental factors. Genomics is important in the development of drugs, design of new drugs, vaccines and DNA diagnostics. Genomics-based therapeutics include "traditional" small chemical drugs, protein drugs, and gene therapy. Genomics refers to the large-scale investigation of the structure and function of genes. Genomics aids drug discovery and development, agroscience research, and other fields.

Recent Publications by Featured Genomics Companies:

Pubmed Logo
GlaxoSmithKline Oligodendrocytes are a Novel Source of Amyloid Peptide Generation.
Alzheimer's disease is characterised by regional neuronal degeneration,...
Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Neurochem Res. 2009 Jun 26.
DOI Direct Link
GlaxoSmithKline Tetrahydrocarbazole amides with potent activity against human papillomaviruses.
Synthesis of a series of tetrahydrocarbazole amides with potent activity...
Department of Medicinal Chemistry, Infectious Diseases Center of Bioorg Med Chem Lett. 2009 Jun 6.
DOI Direct Link
GlaxoSmithKline Oligodendrocytes are a Novel Source of Amyloid Peptide Generation.
Alzheimer's disease is characterised by regional neuronal degeneration,...
Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Neurochem Res. 2009 Jun 26.
DOI Direct Link
GlaxoSmithKline Tetrahydrocarbazole amides with potent activity against human papillomaviruses.
Synthesis of a series of tetrahydrocarbazole amides with potent activity...
Department of Medicinal Chemistry, Infectious Diseases Center of Bioorg Med Chem Lett. 2009 Jun 6.
DOI Direct Link
GSK Differential Effects of p38 MAPK and COX2 Inhibitors in a Model of Cardiovascular Disease.
Aim: There is compelling evidence for a role of inflammation in...
GSK Pharmaceuticals. J Pharmacol Exp Ther. 2009 Jun 25.
DOI Direct Link
AstraZeneca Pharmaceuticals Reexamining transaminase elevation in Phase I clinical trials: the importance of baseline and change from baseline.
PURPOSE: The aims of the present analysis were to determine prevalence of...
AstraZeneca Pharmaceuticals LP, FOC, W1-462 A, 1800 Concord Pike, PO Box Eur J Clin Pharmacol. 2009 Jun 25.
DOI Direct Link
GlaxoSmithKline Medicines Research Centre Intramolecular Hydroamination of Aminoalkenes by Calcium and Magnesium Complexes: A Synthetic and Mechanistic Study.
The beta-diketiminate-stabilized calcium amide complex...
Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, J Am Chem Soc. 2009 Jun 24.
DOI Direct Link

Patents:

USPTO logo
CompanyUS Patent No.Title
Syngenta 7550652 Watermelon pollenizer SP-4
Syngenta 7550578 Rice promoters for regulation of plant expression
GlaxoSmithKline 7550498 1,2-Diaza-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
GlaxoSmithKline 7550498 1,2-Diaza-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
AstraZeneca 7550495 Compounds, compositions containing them, preparation thereof and uses thereof I
GlaxoSmithKline 7549186 Toothbrush
GlaxoSmithKline 7549186 Toothbrush
AstraZeneca 7547789 Process for the preparation of N-(4-piperidinyl)-N-ethyl-phenylacetamides from N-Boc-4-oxopiperidine
AstraZeneca 7547722 Chemical compounds
GlaxoSmithKline 7547679 Ether linked macrolides useful for the treatment of microbial infections

Latest Genomics Publications:
Transgene constructs lacking transcription termination signal induce efficient silencing of endogenous targets in Arabidopsis.
Efficient gene silencing tools are extremely important for genomics and ...
Nicholson SJ, Srivastava V,
http://dx.doi.org/10.1007/s00438-009-0467-1
Mol Genet Genomics. 2009 Jul 1.
Molecular cloning of fungal xylanases: an overview.
Xylanases have received great attention in the development of ...
Ahmed S, Riaz S, Jamil A,
http://dx.doi.org/10.1007/s00253-009-2079-4
Appl Microbiol Biotechnol. 2009 Jul 1.
HPGD mutations cause cranioosteoarthropathy but not autosomal dominant digital clubbing.
Cranio-osteoarthropathy, clinically classified as a variant of primary ...
Seifert W, Beninde J, Hoffmann K, Lindner TH, Bassir C, Aksu F, Hubner C, Verbeek NE, Mundlos S, Horn D,
http://dx.doi.org/10.1038/ejhg.2009.104
Eur J Hum Genet. 2009 Jul 1.
Sample Type Bias in the Analysis of Cancer Genomes.
There is widespread agreement that cancer gene discovery requires ...
Solomon DA, Kim JS, Ressom HW, Sibenaller Z, Ryken T, Jean W, Bigner D, Yan H, Waldman T,
http://dx.doi.org/10.1158/0008-5472.CAN-09-1055
Cancer Res. 2009 Jun 30.
Phylogeny of the CDC25 homology domain reveals rapid differentiation of Ras pathways between early animals and fungi.
The members of the Ras-like superfamily of small GTP-binding proteins are ...
van Dam TJ, Rehmann H, Bos JL, Snel B,
http://dx.doi.org/10.1016/j.cellsig.2009.06.004
Cell Signal. 2009 Jun 27.
Genomic linkage map of the human blood fluke Schistosoma mansoni.
ABSTRACT: BACKGROUND: Schistosoma mansoni is a blood fluke that infects ...
Criscione CD, Valentim CL, Hirai H, Loverde PT, Anderson TJ,
http://dx.doi.org/10.1186/gb-2009-10-6-r71
Genome Biol. 2009 Jun 30;10(6):R71.
Genomic and post-genomic analyses of human prion diseases.
ABSTRACT : Prion diseases share common features of neurodegenerative ...
Pocchiari M, Poleggi A, Principe S, Graziano S, Cardone F,
http://dx.doi.org/10.1186/gm63
Genome Med. 2009 Jun 22;1(6):63.
Brain Cytokines as Neuromodulators in Cardiovascular Control.
1. The role of cytokines in cardiovascular control, especially in ...
Shi P, Raizada MK, Sumners C,
http://dx.doi.org/10.1111/j.1440-1681.2009.05234.x
Clin Exp Pharmacol Physiol. 2009 Jun 29.
What can asexual lineage age tell us about the maintenance of sex?
Sexual reproduction is both extremely costly and extremely common relative ...
Neiman M, Meirmans S, Meirmans PG,
http://dx.doi.org/10.1111/j.1749-6632.2009.04572.x
Ann N Y Acad Sci. 2009 Jun;1168:185-200.
Going adaptive: the saga of antibodies.
Because of their extreme importance to human health, we probably know more ...
Danilova N, Amemiya CT,
http://dx.doi.org/10.1111/j.1749-6632.2009.04881.x
Ann N Y Acad Sci. 2009 Jun;1168:130-55.
2009 | 2008 | 2007 | 2006 | 2005 | 2004 |