l

 Home l UK Companies l Genomics Topics l Species with sequenced Genomes l Contact

l
Thursday 11th March 2010 04:27 PM This Month's Genome Publications

Genomics refers to the study of genes and their function. Genomics leads to an understanding of the molecular mechanisms of disease, including the complex interplay of genetic and environmental factors. Genomics is important in the development of drugs, design of new drugs, vaccines and DNA diagnostics. Genomics-based therapeutics include "traditional" small chemical drugs, protein drugs, and gene therapy. Genomics refers to the large-scale investigation of the structure and function of genes. Genomics aids drug discovery and development, agroscience research, and other fields.

Recent Publications by Featured Genomics Companies:

Pubmed Logo
Cell Cycle Laboratory Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns.
Although the basic mechanisms of DNA synthesis are conserved across...
Cell Cycle Laboratory, London Research Institute, Blanche Lane, EMBO Rep. 2010 Feb 26.
DOI Direct Link
GlaxoSmithKline Novel bis-phenanthridine derivatives with easily tunable linkers, study of their interactions with DNA and screening of antiproliferative activity.
Series of novel peptide-bridged bis-phenanthridine derivatives as well as...
Division of Organic Chemistry and Biochemistry, Ruder Boskovic Institute, Eur J Med Chem. 2010 Feb 12.
DOI Direct Link
GlaxoSmithKline Reduced proliferation of non-megakaryocytic acute myelogenous leukemia and other leukemia and lymphoma cell lines in response to eltrombopag.
Leukemia cell lines were treated with eltrombopag or thrombopoietin and...
Oncology Translational Research, GlaxoSmithKline, 1250 South Collegeville Leuk Res. 2010 Mar 2.
DOI Direct Link
Merck Sharp & Dohme Research Laboratories Long-Term Assessment of Asenapine vs. Olanzapine in Patients with Schizophrenia or Schizoaffective Disorder.
INTRODUCTION: We conducted a double-blind 1-year trial of asenapine in...
Schering-Plough (formerly NV Organon), now Merck Sharp & Dohme, Oss, The Pharmacopsychiatry. 2010 Mar 4.
DOI Direct Link
GlaxoSmithKline Novel bis-phenanthridine derivatives with easily tunable linkers, study of their interactions with DNA and screening of antiproliferative activity.
Series of novel peptide-bridged bis-phenanthridine derivatives as well as...
Division of Organic Chemistry and Biochemistry, Ruder Boskovic Institute, Eur J Med Chem. 2010 Feb 12.
DOI Direct Link
GlaxoSmithKline Reduced proliferation of non-megakaryocytic acute myelogenous leukemia and other leukemia and lymphoma cell lines in response to eltrombopag.
Leukemia cell lines were treated with eltrombopag or thrombopoietin and...
Oncology Translational Research, GlaxoSmithKline, 1250 South Collegeville Leuk Res. 2010 Mar 2.
DOI Direct Link
Pfizer Global Research and Development Orally active and brain permeable proline amides as highly selective 5HT2c agonists for the treatment of obesity.
Brain-penetrable proline amides were developed as 5HT2c agonists with more...
Pfizer Global Research and Development, Chemistry Department, 10770 Bioorg Med Chem Lett. 2010 Jan 25.
DOI Direct Link

Patents:

USPTO logo
CompanyUS Patent No.Title
Syngenta 7671257 Inbred corn line G07-NPDI4214
AstraZeneca 7671195 Process for preparing dibenzothiazepine compounds
AstraZeneca 7671060 Heteroaryl benzamide derivatives
AstraZeneca 7670625 Pharmaceutical composition containing an active ingredient and a micronised carrier/diluent
AstraZeneca 7670591 Heteroaryl substituted benzoxazoles
Forensic Science Service 7668660 Analysis of DNA
Syngenta 7667108 Inbred corn line G07-NPFA7278
GlaxoSmithKline 7666988 BASB082 Polypeptides
GlaxoSmithKline 7666988 BASB082 Polypeptides
AstraZeneca 7666892 Metalloproteinase inhibitors

Latest Genomics Publications:
Nanoparticle-aptamer conjugates for cancer cell targeting and detection.
Aptamers are DNA or RNA oligonucleotide sequences that selectively bind to ...
Estevez MC, Huang YF, Kang H, O'Donoghue MB, Bamrungsap S, Yan J, Chen X, Tan W,
http://dx.doi.org/10.1007/978-1-60761-609-2_16
Methods Mol Biol. 2010;624:235-48.
Transfection of siRNAs in Multiple Myeloma Cell Lines.
RNA interference (RNAi), a valuable tool to specifically silence gene ...
Brito JL, Brown N, Morgan GJ,
http://dx.doi.org/10.1007/978-1-60761-588-0_19
Methods Mol Biol. 2010;623:299-309.
Nonviral siRNA Delivery for Gene Silencing in Neurodegenerative Diseases.
Linking genes with the underlying mechanisms of diseases is one of the ...
Prakash S, Malhotra M, Rengaswamy V,
http://dx.doi.org/10.1007/978-1-60761-588-0_14
Methods Mol Biol. 2010;623:211-29.
Computational siRNA Design Considering Alternative Splicing.
RNA interference (RNAi) with small interfering RNA (siRNA) has become a ...
Kim YJ,
http://dx.doi.org/10.1007/978-1-60761-588-0_5
Methods Mol Biol. 2010;623:81-92.
Proteomics and islet research.
The complementary disciplines of genomics and proteomics offer better ...
Ahmed M,
http://dx.doi.org/10.1007/978-90-481-3271-3_16
Adv Exp Med Biol. 2010;654:363-90.
Non-coding small RNAs responsive to abiotic stress in wheat (Triticum aestivum L.).
Plant small RNAs are emerging as significant components of epigenetic ...
Yao Y, Ni Z, Peng H, Sun F, Xin M, Sunkar R, Zhu JK, Sun Q,
http://dx.doi.org/10.1007/s10142-010-0163-6
Funct Integr Genomics. 2010 Mar 9.
Genome-wide association studies for blood lipids. A great start but a long way to go. School of Medicine, National University of Singapore bDuke-National University of Singapore Graduate Medical School, Singapore, Singapore cNutrition and Genomics Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA dDepartment of Epidemiology and Population Genetics, Centro Nacional Investigacion Cardiovascular (CNIC), Madrid, Spain. Tai ES, Ordovas JM,
http://dx.doi.org/10.1097/MOL.0b013e32833851d0
Curr Opin Lipidol. 2010 Mar 5.
Improving nursing practice with genomics. nurse specialist and assistant professor, Katherine F. Burbank is a maternal-fetal medicine nurse in high-risk obstetrics and a perinatal educator, and Laura M. Junglen is a staff nurse in pulmonary and critical care medicine. Pestka EL, Burbank KF, Junglen LM,
http://dx.doi.org/10.1097/01.NUMA.0000369499.99852.c3
Nurs Manage. 2010 Mar;41(3):40-4.
The kidney transplant: new horizons.
PURPOSE OF REVIEW: In renal transplantation, significant improvements in ...
Mengel M,
http://dx.doi.org/10.1097/MNH.0b013e3283381ea5
Curr Opin Nephrol Hypertens. 2010 Mar 3.
A platform for functional prediction and comparative analyses of transcription factors of legumes and beyond.
Sequence-specific DNA-binding transcription factors (TFs) are key ...
Tran LS, Mochida K,
Plant Signal Behav. 2010 May 28;5(5).
2010 | 2009 | 2008 | 2007 | 2006 | 2005 |