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Systems biology, metabolic modelling and metabolomics in drug discovery and development.
Unlike signalling pathways, metabolic networks are subject to strict ...
Kell DB,
http://dx.doi.org/10.1016/j.drudis.2006.10.004
Drug Discov Today. 2006 Dec;11(23-24):1085-92. Epub 2006 Oct 19.
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Biochemical and molecular characterization of flavonoid 7-sulfotransferase from Arabidopsis thaliana.
Flavonoid compounds play important roles as flower pigments, stress ...
Gidda SK, Varin L,
http://dx.doi.org/10.1016/j.plaphy.2006.10.004
Plant Physiol Biochem. 2006 Nov-Dec;44(11-12):628-36. Epub 2006 Oct 19.
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Parallel processing of large datasets from NanoLC-FTICR-MS measurements.
A new approach for automatic parallel processing of large mass spectral ...
van der Burgt YE, Taban IM, Konijnenburg M, Biskup M, Duursma MC, Heeren RM, Rompp A, van Nieuwpoort RV, Bal HE,
http://dx.doi.org/10.1016/j.jasms.2006.09.005
J Am Soc Mass Spectrom. 2007 Jan;18(1):152-61. Epub 2006 Oct 19.
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Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells.
An understanding of the regulatory mechanisms responsible for pluripotency ...
Sun Y, Li H, Liu Y, Shin S, Mattson MP, Rao MS, Zhan M,
http://dx.doi.org/10.1016/j.ygeno.2006.09.010
Genomics. 2007 Jan;89(1):22-35. Epub 2006 Oct 19.
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Bioorthogonal noncovalent chemistry: Fluorous phases in chemical biology.
Chemical entities designed to noncovalently interact with predetermined ...
Yoder NC, Yuksel D, Dafik L, Kumar K,
http://dx.doi.org/10.1016/j.cbpa.2006.10.007
Curr Opin Chem Biol. 2006 Dec;10(6):576-83. Epub 2006 Oct 19.
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The evolution and genomic landscape of CGB1 and CGB2 genes.
The origin of completely novel proteins is a significant question in ...
Hallast P, Rull K, Laan M,
http://dx.doi.org/10.1016/j.mce.2005.11.049
Mol Cell Endocrinol. 2007 Jan 2;260-262:2-11. Epub 2006 Oct 19.
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Protein-protein interaction analysis using an affinity peptide tag and hydrophilic polystyrene plate.
A sandwich ELISA method using peptide tags showing a specific affinity to ...
Kumada Y, Zhao C, Ishimura R, Imanaka H, Imamura K, Nakanishi K,
http://dx.doi.org/10.1016/j.jbiotec.2006.09.018
J Biotechnol. 2007 Feb 1;128(2):354-61. Epub 2006 Oct 19.
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Obestatin does not activate orphan G protein-coupled receptor GPR39.
Recently, the ligand of the orphan G protein-coupled receptor GPR39 has ...
Lauwers E, Landuyt B, Arckens L, Schoofs L, Luyten W,
http://dx.doi.org/10.1016/j.bbrc.2006.09.141
Biochem Biophys Res Commun. 2006 Dec 8;351(1):21-5. Epub 2006 Oct 19.
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Fused kinase is stabilized by Cdc37/Hsp90 and enhances Gli protein levels.
Serine/threonine kinase Fused (Fu) is an essential component of Hedgehog ...
Kise Y, Takenaka K, Tezuka T, Yamamoto T, Miki H,
http://dx.doi.org/10.1016/j.bbrc.2006.10.036
Biochem Biophys Res Commun. 2006 Dec 8;351(1):78-84. Epub 2006 Oct 19.
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Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling.
The conserved polarity complex, comprising the partitioning-defective ...
Wang Y, Du D, Fang L, Yang G, Zhang C, Zeng R, Ullrich A, Lottspeich F, Chen Z,
http://dx.doi.org/10.1038/sj.emboj.7601384
EMBO J. 2006 Nov 1;25(21):5058-70. Epub 2006 Oct 19.
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