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Defining and characterizing protein surface using alpha shapes.
The alpha shape of a molecule is a geometrical representation that ...
Albou LP, Schwarz B, Poch O, Wurtz JM, Moras D,
http://dx.doi.org/10.1002/prot.22301
Proteins. 2008 Oct 21.
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An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene. Canada. Tempel W, Wu H, Dombrovsky L, Zeng H, Loppnau P, Zhu H, Plotnikov AN, Bochkarev A,
http://dx.doi.org/10.1002/prot.22299
Proteins. 2008 Oct 21;74(3):789-793.
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The fast-folding HP35 double mutant has a substantially reduced primary folding free energy barrier.
The LYS24/29NLE double mutant of villin headpiece subdomain (HP35) is the ...
Lei H, Deng X, Wang Z, Duan Y,
http://dx.doi.org/10.1063/1.2995987
J Chem Phys. 2008 Oct 21;129(15):155104.
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The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases.
Whereas medicine is currently undergoing remarkable developments from its ...
Boccia S, Brand A, Brand H, Ricciardi G,
http://dx.doi.org/10.1016/j.mrfmmm.2008.10.003
Mutat Res. 2008 Oct 21.
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Human receptor for activated protein kinase C1 associates with polyglutamine aggregates and modulates polyglutamine toxicity.
Formation of SDS-insoluble protein aggregates in affected neurons is a ...
Lam W, Chan WM, Lo TW, Wong AK, Wu CC, Chan HY,
http://dx.doi.org/10.1016/j.bbrc.2008.10.057
Biochem Biophys Res Commun. 2008 Dec 12;377(2):714-9. Epub 2008 Oct 21.
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Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.
The presenilin/gamma-secretase complex, an unusual intramembrane aspartyl ...
Hemming ML, Elias JE, Gygi SP, Selkoe DJ,
http://dx.doi.org/10.1371/journal.pbio.0060257
PLoS Biol. 2008 Oct 21;6(10):e257.
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Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse.
To generate temporally-controlled targeted somatic mutations selectively ...
Wendling O, Bornert JM, Chambon P, Metzger D,
http://dx.doi.org/10.1002/dvg.20448
Genesis. 2008 Oct 21.
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Mir-144 selectively regulates embryonic {alpha}-hemoglobin synthesis during primitive erythropoiesis.
Precise transcriptional control of developmental stage-specific expression ...
Fu YF, Du TT, Dong M, Zhu KY, Jing CB, Zhang Y, Wang L, Fan HB, Chen Y, Jin Y, Yue GP, Chen SJ, Chen Z, Huang QH, Jing Q, Deng M, Liu TX,
http://dx.doi.org/10.1182/blood-2008-08-174854
Blood. 2008 Oct 21.
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Evolutionary redefinition of immunoglobulin light chain isotypes in tetrapods using molecular markers.
The phylogenetic relationships of Ig light chain (IGL) genes are difficult ...
Das S, Nikolaidis N, Klein J, Nei M,
http://dx.doi.org/10.1073/pnas.0808800105
Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16647-52. Epub 2008 Oct 21.
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Optimization of experimental design parameters for high-throughput chromatin immunoprecipitation studies.
High-throughput, microarray-based chromatin immunoprecipitation ...
Ponzielli R, Boutros PC, Katz S, Stojanova A, Hanley AP, Khosravi F, Bros C, Jurisica I, Penn LZ,
http://dx.doi.org/10.1093/nar/gkn735
Nucleic Acids Res. 2008 Dec;36(21):e144. Epub 2008 Oct 21.
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