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Recent Publications by GlaxoSmithKline Pharmaceuticals: |  | |
| Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1.
The ion channel TRPA1 is activated by a wide variety of noxious stimuli,... | Neuronal Targets DPU, Respiratory Therapy Area Unit, GlaxoSmithKline | Neurosci Lett. 2011 Oct 10;503(3):157-62. Epub 2011 Aug 10.
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| Investigations into the environmental conditions experienced during ambient sample transport: impact to dried blood spot sample shipments.
BACKGROUND: Prior to bioanalysis, sample transport and storage are... | Platform Technology & Science, GlaxoSmithKline Pharmaceuticals, King of | Bioanalysis. 2011 Jul;3(14):1625-33.
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| Pyridine-derived gamma-secretase modulators.
SAR of a novel series of pyridine-derived gamma-secretase modulators is... | Research and Development, GlaxoSmithKline Pharmaceuticals, 898 Halei Road, | Bioorg Med Chem Lett. 2011 Aug 15;21(16):4832-5. Epub 2011 Jun 17.
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| Pyridazine-derived gamma-secretase modulators.
SAR of a novel series of pyridazine-derived gamma-secretase modulators is... | Research and Development, GlaxoSmithKline Pharmaceuticals, 898 Halei Road, | Bioorg Med Chem Lett. 2011 Jul 1;21(13):4016-9. Epub 2011 May 13.
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| NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation.
NADPH oxidase isoform-2 (NOX2) generates reactive oxygen species (ROS)... | Metabolic Pathways and Cardiovascular Therapeutic Area Unit , | J Enzyme Inhib Med Chem. 2011 Dec 3.
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