|
Loading...
| ||||||||||||||
Recent Publications by GlaxoSmithKline Pharmaceuticals: |  | |
| An excitatory role for peripheral EP3 receptors in bladder afferent function.
The excitatory roles of EP3 receptors at the peripheral afferent nerve... | Department of Urology, GlaxoSmithKline Pharmaceuticals, King of Prussia, | Am J Physiol Renal Physiol. 2008 Aug;295(2):F585-94. Epub 2008 Jun 18.
DOI Direct Link |
| Chemical mechanism of a cysteine protease, cathepsin C, as revealed by integration of both steady-state and pre-steady-state solvent kinetic isotope effects.
Cathepsin C, or dipeptidyl peptidase I, is a lysosomal cysteine protease... | Department of Biological Reagents and Assay Development and Discovery | Biochemistry. 2008 Aug 19;47(33):8697-710. Epub 2008 Jul 26.
DOI Direct Link |
| Potent and selective small-molecule human urotensin-II antagonists with improved pharmacokinetic profiles.
Lead compound 1 was successfully redesigned to provide compounds with... | Department of Medicinal Chemistry, Cardiovascular and Urogenital Center of | Bioorg Med Chem Lett. 2008 Jul 1;18(13):3716-9. Epub 2008 May 20.
DOI Direct Link |
| A Bayesian approach to the ICH Q8 definition of design space.
Manufacturers of pharmaceuticals and biopharmaceuticals are facing... | GlaxoSmithKline Pharmaceuticals, Collegeville, Pennsylvania 19426, USA. | J Biopharm Stat. 2008;18(5):959-75.
DOI Direct Link |
| Comparison of non-digitalis binding properties of digoxin-specific Fabs using direct binding methods.
Digibind and DigiFab are commercial formulations of polyclonal, ovine,... | Department of Biochemistry, Cardiovascular and Urogenital Center of | J Immunol Methods. 2008 Jul 31;336(2):235-41. Epub 2008 Jun 4.
DOI Direct Link |