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GlaxoSmithKline Pharmaceuticals

Contact Details:
Address:Discovery and Analysis Bioinformatics
GlaxoSmithKline Pharmaceuticals
Harlow
Essex
Postcode:CM19 5AW
Country:UK

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Recent Publications by GlaxoSmithKline Pharmaceuticals:

Identification of germline competent chimaeras by copulatory plug genotyping.
The increasing use of ES cell lines from strains other than 129, in...
Molecular Discovery Research, GlaxoSmithKline Pharmaceuticals, New Transgenic Res. 2010 Jun 12.
DOI Direct Link
Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists.
A series of 3-aryl-4-isoxazolecarboxamides identified from a...
Discovery Medicinal Chemistry, Discovery Research, GlaxoSmithKline Bioorg Med Chem Lett. 2010 Feb 15;20(4):1363-7. Epub 2010 Jan 7.
DOI Direct Link
Asking complex questions of the genome without programming.
Increasingly, vast amounts of genomics and genetic data are available....
Computational Biology, Quantitative Sciences, GlaxoSmithKline Methods Mol Biol. 2010;628:39-52.
DOI Direct Link
Improving the developability profile of pyrrolidine progesterone receptor partial agonists.
The previously reported pyrrolidine class of progesterone receptor partial...
Department of Chemistry, Metabolic Pathways Centre for Excellence in Drug Bioorg Med Chem Lett. 2010 Jan 1;20(1):371-4. Epub 2009 Oct 25.
DOI Direct Link
Treatment with a potent cathepsin K inhibitor preserves cortical and trabecular bone mass in ovariectomized monkeys.
The cysteine protease cathepsin K is involved in osteoclast-mediated bone...
Department of Musculoskeletal Diseases, GlaxoSmithKline Pharmaceuticals, Calcif Tissue Int. 2009 Oct;85(4):344-55. Epub 2009 Sep 10.
DOI Direct Link