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Recent Publications by GlaxoSmithKline Pharmaceuticals: |  | |
| Identification of germline competent chimaeras by copulatory plug genotyping.
The increasing use of ES cell lines from strains other than 129, in... | Molecular Discovery Research, GlaxoSmithKline Pharmaceuticals, New | Transgenic Res. 2010 Jun 12.
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| Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists.
A series of 3-aryl-4-isoxazolecarboxamides identified from a... | Discovery Medicinal Chemistry, Discovery Research, GlaxoSmithKline | Bioorg Med Chem Lett. 2010 Feb 15;20(4):1363-7. Epub 2010 Jan 7.
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| Asking complex questions of the genome without programming.
Increasingly, vast amounts of genomics and genetic data are available.... | Computational Biology, Quantitative Sciences, GlaxoSmithKline | Methods Mol Biol. 2010;628:39-52.
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| Improving the developability profile of pyrrolidine progesterone receptor partial agonists.
The previously reported pyrrolidine class of progesterone receptor partial... | Department of Chemistry, Metabolic Pathways Centre for Excellence in Drug | Bioorg Med Chem Lett. 2010 Jan 1;20(1):371-4. Epub 2009 Oct 25.
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| Treatment with a potent cathepsin K inhibitor preserves cortical and trabecular bone mass in ovariectomized monkeys.
The cysteine protease cathepsin K is involved in osteoclast-mediated bone... | Department of Musculoskeletal Diseases, GlaxoSmithKline Pharmaceuticals, | Calcif Tissue Int. 2009 Oct;85(4):344-55. Epub 2009 Sep 10.
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