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Recent Publications by Oxagen Ltd.: |  | |
| Antagonists of the prostaglandin D(2) receptor CRTH2.
Prostaglandin D(2) (PGD(2)) is produced by mast cells, Th2 lymphocytes and... | Oxagen | Drug News Perspect. 2008 Jul-Aug;21(6):317-22.
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| The roles of the prostaglandin D(2) receptors DP(1) and CRTH2 in promoting allergic responses.
Prostaglandin D(2) (PGD(2)) is produced by mast cells, Th2 lymphocytes and... | Oxagen Ltd, 91 Milton | Br J Pharmacol. 2008 Mar;153 Suppl 1:S191-9. Epub 2007 Oct 29.
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| A paracrine role for chemoattractant receptor-homologous molecule expressed on T helper type 2 cells (CRTH2) in mediating chemotactic activation of CRTH2+ CD4+ T helper type 2 lymphocytes.
Activation of human CRTH2(+) CD4(+) T helper type 2 (Th2) cells with... | Department of Drug Discovery, Oxagen Ltd, Abingdon, Oxon, United Kingdom. | Immunology. 2007 Aug;121(4):577-84. Epub 2007 Apr 16.
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| A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants.
Human cultured mast cells, immunologically activated with immunoglobuin E... | Department of Drug Discovery, Oxagen Ltd, Abingdon, Oxon, United Kingdom. | Immunology. 2006 Nov;119(3):362-8.
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| Identification of G-protein-coupled receptors involved in inflammatory disease by genetic association studies.
G-protein-coupled receptors are not only highly tractable drug targets but... | Department of Drug and Target Discovery, Oxagen Ltd, 91 Milton Park, | Curr Opin Pharmacol. 2005 Aug;5(4):412-7.
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