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Genomic Health

Recent Publications on genomic health :

Semi-quantitative immunohistochemical assay versus oncotype DX((R)) qRT-PCR assay for estrogen and progesterone receptors: an independent quality assurance study.
Estrogen receptor (ER) status is a strong predictor of response to...
Department of Pathology, Pittsburgh, PA, USA. Mod Pathol. 2012 Feb 3. doi: 10.1038/modpathol.2011.219.
DOI Direct Link
Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer.
PURPOSE: We recently reported that the mRNA-based, 21-gene Genomic Health...
Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, J Clin Oncol. 2011 Nov 10;29(32):4273-8. Epub 2011 Oct 11.
DOI Direct Link
High false-negative rate of HER2 quantitative reverse transcription polymerase chain reaction of the Oncotype DX test: an independent quality assurance study.
PURPOSE: HER2 (ERBB2) status is an important prognostic and predictive...
Magee-Womens Hospital of UPMC, 300 Halket St, Pittsburgh, PA, USA. J Clin Oncol. 2011 Nov 10;29(32):4279-85. Epub 2011 Oct 11.
DOI Direct Link
Association of direct-to-consumer genome-wide disease risk estimates and self-reported disease.
The ongoing controversy surrounding direct-to-consumer (DTC) personal...
Scripps Genomic Medicine, Scripps Translational Science Institute, La Genet Epidemiol. 2011 Nov 29. doi: 10.1002/gepi.20664.
DOI Direct Link
Chromobility: the rapid movement of chromosomes in interphase nuclei.
There are an increasing number of studies reporting the movement of gene...
Laboratory of Nuclear and Genomic Health, Centre of Cell and Chromosome Biochem Soc Trans. 2011 Dec;39(6):1747-51.
DOI Direct Link

Patents:

US Patent No.Title
8097423 MN/CA IX and breast cancer therapy
7838224 Gene expression profiling in biopsied tumor tissues
7767391 Use of intronic RNA to measure gene expression
7723050 Diabetes-related biomarkers and methods of use thereof
7723033 Prediction of likelihood of cancer recurrence