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Genomics Novartis

Recent Publications on genomics novartis :

Antigen identification starting from the genome: a "Reverse Vaccinology" approach applied to MenB.
Most of the vaccines available today, albeit very effective, have been...
Novartis Vaccines and Diagnostics, Siena, Italy. Methods Mol Biol. 2012;799:361-403.
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Kinase inhibitor profiling using chemoproteomics.
Quantitative chemoproteomics has recently emerged as an experimental...
Novartis Institutes for Biomedical Research, Cambridge, MA, USA. Methods Mol Biol. 2012;795:161-77.
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Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824.
Tuberculosis continues to be a global health threat, making bicyclic...
Genomics Institute of the Novartis Research Foundation, 10675 John Jay Structure. 2012 Jan 11;20(1):101-12.
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Simultaneous Purification and Site-Specific Modification of Pyrroline-Carboxy-Lysine Proteins.
Sticky residue: Pyrroline-carboxy-lysine (Pcl) can be readily incorporated...
Genomics Institute of the Novartis Research Foundation, 10675 Chembiochem. 2012 Jan 5. doi: 10.1002/cbic.201100684.
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Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization.
The tad (tight adherence) locus encodes a protein translocation system...
Joint Center for Structural Genomics, http://www.jcsg.org Mol Microbiol. 2012 Feb;83(4):712-727. doi:
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