Recent Publications on genomics novartis : |  | |
| Malaria research in the post-genomic era.
For many pathogens the availability of genome sequence, permitting... | Genomics Institute of the Novartis Research Foundation, San Diego, | Nature. 2008 Oct 9;455(7214):751-6.
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| The Polymerase Incomplete Primer Extension (PIPE) Method Applied to High-Throughput Cloning and Site-Directed Mutagenesis.
Significant innovations in molecular biology methods have vastly improved... | The Genomics Institute of the Novartis Research Foundation, San Diego, CA, | Methods Mol Biol. 2009;498:91-103.
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| Optimization of small molecule agonists of the thrombopoietin (Tpo) receptor derived from a benzo[a]carbazole hit scaffold.
The lead optimization of a novel series of benzo[a]carbazole-based small... | Genomics Institute of the Novartis Research Foundation (GNF), San Diego, | Bioorg Med Chem Lett. 2008 Oct 1;18(19):5259-62. Epub 2008 Aug 26.
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| Discovery and biological evaluation of benzo[a]carbazole-based small molecule agonists of the thrombopoietin (Tpo) receptor.
A novel series of benzo[a]carbazole-based small molecule agonists of the... | Genomics Institute of the Novartis Research Foundation (GNF), San Diego, | Bioorg Med Chem Lett. 2008 Oct 1;18(19):5255-8. Epub 2008 Aug 22.
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| Snapshot PK: a rapid rodent in vivo preclinical screening approach.
Described in this article are strategies implemented to increase the... | Department of Pharmacology, Genomics Institute of the Novartis Research | Drug Discov Today. 2008 Apr;13(7-8):360-7. Epub 2007 Nov 26.
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